- JOB
- Spain
Job Information
- Organisation/Company
- BIOGIPUZKOA HEALTH RESEARCH INSTITUTE
- Research Field
- Biological sciences » Biology
- Researcher Profile
- Recognised Researcher (R2)
- Positions
- Postdoc Positions
- Country
- Spain
- Application Deadline
- Type of Contract
- Temporary
- Job Status
- Full-time
- Hours Per Week
- 35
- Offer Starting Date
- Is the job funded through the EU Research Framework Programme?
- Not funded by a EU programme
- Is the Job related to staff position within a Research Infrastructure?
- No
Offer Description
We are offering a contract for a Postdoctoral Researcher in Neurosciences or related disciplines. The candidate will join our dynamic Neurodegenerative Diseases Group at the Department of Neurosciences, Biogipuzkoa Health Research Institute, and will focus on the identification and characterization of new pathological mechanisms in Neurodegenerative diseases, particularly Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD), as part of the IKUR-Neurobiociencias 2025-2026 project: "NB1. Neuromotortherapy. Searching multitarget therapies against TDP-43 dysfunction in Familial Frontotemporal Dementia and Amyotrophic Lateral Sclerosis."
The project will tackle the pathology from multiple fronts, using in vivo and in vitro approaches, including Drosophila melanogaster animal models, and advancing to neurons differentiated from pluripotent stem cells derived from ALS/FTD patients. The goal is to unravel and modulate the underlying pathological mechanisms through innovative therapeutic strategies. In addition to testing new, potentially effective therapeutic treatments, the researcher will generate and characterize different gene-silencing and overexpression models in both in vivo and in vitro settings to deeply explore and understand these disease mechanisms.
The selected candidate will work with cutting-edge techniques in cell and molecular biology, as well as advanced imaging technologies, in a world-class research environment. The researcher will contribute actively to the group's objectives and will also have the opportunity and support to develop independent projects that expand and strengthen our ALS/FTD research line.
Position Location: Biogipuzkoa Health Research Institute (San Sebastián).
Where to apply
Requirements
- Research Field
- Biological sciences » Biology
- Education Level
- PhD or equivalent
ESSENTIAL REQUIREMENTS:
- Consolidated PhD in Neuroscience, Molecular Biology, Biomedicine, or a closely related field, with a track record of relevant publications.
- Demonstrable and deep experience in cell and molecular biology applied to neurodegenerative disease models, with a particular focus on ALS.
- Evidence of laboratory experience with Drosophila melanogaster in neurodegenerative diseases.
- Functional and molecular biology assays experience, including the generation and characterization of double and triple transgenic models.
- Advanced experience in handling complex animal models (preferably Drosophila melanogaster) and culturing human neuronal cells (including iPSCs or primary models).
- Experience in pharmacological and genetic modification of Drosophila strains.
- Expert knowledge of advanced imaging techniques, such as confocal microscopy, fluorescence, and/or super-resolution microscopy, with the ability to perform quantitative image analysis.
- Exceptional skills in analyzing experimental data, with proficiency in statistical and computational analysis tools (Python, R, MATLAB, etc.).
- Experience in cell metabolism studies.
- Excellent command of written and spoken English, with a proven track record of writing and publishing scientific papers in high-impact journals.
- Strong strategic interest and motivation for translational research and therapeutic validation in the field of neurodegenerative diseases, specifically ALS.
- Proven ability to work independently and as part of a high-performance multidisciplinary team.
WILL BE CONSIDERED A PLUS:
- Experience in bioinformatics applied to omics data (genomics, transcriptomics).
- Knowledge in the design and management of drug screening or therapeutic assays.
- Experience in project funding (grant application and management).
- Strong communication and presentation skills in international scientific environments.
- Possession of a disability certificate of 33% or higher.
- Languages
- ENGLISH
- Level
- Excellent
- Research Field
- Biological sciences » Biology
- Years of Research Experience
- 1 - 4
Additional Information
- TYPE OF CONTRACT: 36-month Postdoctoral Access contract with the possibility of an extension.
- TIPE OF WORKDAY: Full-time
- EXPECTED START DATE: July 2025
- ANNUAL GROSS SALARY: 29.000€ - 32.000€ gross per year.
The remuneration will be assigned based on the candidate's dedication, merit, and suitability for the offered position. The employee must adhere to the internal rules and regulations of the Biogipuzkoa Institute regarding dedication, the role to be performed, working hours, leave, etc.
Applications meeting the REQUIRED competencies in the job posting will be evaluated.
- EXPERIENCE (0-30 PTS)
- KNOWLEDGE (ACCREDITED) (0-20 PTS)
- LANGUAGES (ENGLISH) (0-20 PTS)
- OTHER MERITS (0-20 PTS)
- CERTIFICATE OF DISABILITY MINIMUM 33% (0-10 PTS)
- INTERVIEW (0-25 PTS)
APPLICATION FORMALIZATION
It is mandatory to apply for the position through the job portal on the IIS Biogipuzkoa website (www.biodonostia.org). No paper documentation will be accepted. All documents must be submitted electronically via this website.
BIOGIPUZKOA is committed to the principles of merit-based recruitment and transparency (OTM-R Policy), in accordance with the requirements of the HRS4R Seal established by the European Commission. Additionally, it has taken on the responsibility of ensuring gender equality through actions outlined in the current Equality Plan.
After the evaluation and selection process, candidates may request information about their scores, as well as the score of the selected candidate.
For any questions or clarifications, please contact via email at rrhh@bio-gipuzkoa.eus
Deadline for CV submission: 07/24/2025
- Website for additional job details
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- ASOCIACIÓN INSTITUTO DE INVESTIGACIÓN SANITARIA BIOGIPUZKOA
- Country
- Spain
- State/Province
- GUIPUZCOA
- City
- SAN SEBASTIAN
- Postal Code
- 20014
- Street
- PASEO DR. BEGUIRISTAIN S/N
Contact
- State/Province
- Gipuzkoa
- City
- San Sebastian
- Website
- Street
- Paseo Dr. Beguiristain
- Postal Code
- 20014
- arantza.abad@biodonostia.org